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Interese stiintifice

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Studii in strainatate:

1996:    Germania, Köln, Universitatea Köln Clinica Neurochirurgie – 2  saptamani

1998-1999:    Germania, Köln, Universitatea Köln Clinica Neurochirurgie,  Laboratorul neuro-oncologic  – 1 an bursa DAAD

2004:    Spania, Alicante, Miguel Hernandez University, Institutul De Anatomie, 2 saptamani

 

Proiecte  acceptate in cercetari:

 

  1. OTKA T-020128/1995, participant, 1996-1999, 1.400mii Ft
    Cond: Dr. Molnár Péter, DE OEC,  Institutul Patologic
  2. ETT 350/1996, participant, 1997-1999, 1.500 mii Ft
    Cond: Dr. Csécsei György, DE OEC, Clinica Neurochirurgie
  3. Mecenatura 2004-2006, participant, 750mii Ft
    Cond: Dr. Felszeghy Szabolcs, DE  OEC, Institutul de Anatomie
  4. ETT:  „Rolul devierilor histopatologice sistematice in diagnosticul precoce al aneurismelor cerebrale”  2003-2005,  3M Ft
    Cond: Dr. Klekner Álmos Péter
  5. OTKA:  „Examinarea rolului EGFR si a integrinelor in invazia tumorala in tumorile intracraniene”,  2005-2008,  6M Ft
    Cond: Dr. Klekner Álmos

 

Lucrari publicate: 13,                       Prezentatii, postere: 33

Factor impact cumulativ: 18.52        Citatii(fara autocitatii): 15.

 

Functii in societati:                      

  • Membru al Societatii  Ungara de Neurochirurgie
  • Membru al Societatii  Ungara de Neuropatologie
  • Membru al Societatii  Ungara  de Neuro-Oncologie
  • Membru al Societatii  Europene de Neurochirurgie

Interese stiintifice:   Laboratorul Neuro-Oncologic

  1. Tratamentul modern al tumorului cerebral – vezi bibliografia 
  • Klekner A, Ernestus RI, Röhn G, Molnár P, Csécsei Gy, Klug N: Polyamine metabolism in ependymomas. Path Int, 46, S1: 625, 1996, IF: 0.748
  • Ernestus RI, Röhn G, Schröder R, Els T, Klekner A, Paschen W, Klug N: Polyamine metabolism in brain tumours: diagnostic relevance of quantitative biochemistry. J Neurol Neurosurg Psychiatry 71: 88-92, 2001, IF: 3.024
  • Klekner A, Röhn G, Schillinger G, Schröder R, Klug N, Ernestus RI: ODC mRNA as a prognostic factor for recurrence in meningiomas. J Neuro-oncol. 53: 67-75, 2001  IF: 1.435
  • Klekner A, Ernestus RI, Röhn G, Molnár P, Csécsei Gy, Klug N: Polyamine metabolism in ependymomas. Path Int, 46, S1: 625, 1996, IF: 0.748
  • Dabasi G, Hauser P, Kertész GP, Balázs G, Karádi Z, Constantin T, Bognar L, Klekner A, Schuler D, Garami M: Imaging of pediatric brain tumors using somatostatin analogue 111Ih-DTPA-D-Phe1-octreotide. Magy Onkol, 2007 51(3):229-234.
  • Klekner A, Varga I, Bognár L, Hutóczki G, Kenyeres A, Tóth J, Hanzély Z, Scholtz B.: Különbözö invazivitású agydaganatok extracelluláris mátrixának expressziója. J Clin Neurosci. Közlésre elfogadva, 2009.03.
  • Petrás M., Varga I., Vereb Gy., Szöllösi J., Hutóczki G., Bognár L., Ruszthi P., Kenyeres A., Tóth J., Hanzély Z., Scholtz B., Klekner Á.: Különbözö eredetü malignus agydaganatok invazivitásának panelszerü vizsgálata. Magyar Onkológia, 2009; 53(3):253-8.
  • Toth J, Egervari K, Klekner A, Bognar L, Szanto J, Nemes Z, Szollosi Z. Analysis of EGFR Gene Amplification,
    Protein Over-expression and Tyrosine Kinase Domain Mutation in Recurrent Glioblastoma. Pathol Oncol Res. 2008 Aug 28. (Epub ahead of print). IF: 1.24

 

  1. Dezvoltarea tehnicii operatorie in bolile degenerativecoloanei  vertebrale – vezi bibliografia
  • Csécsei Gy, Klekner A, Sikula J: Posterior lumbar interbody fusion (PLIF) using the bony elements of the dorsal spinal segment. Acta Chir Hun, 36 (1-4): 54-56, 1997 
  • Csécsei Gy, Klekner A, Dobai J, Lajgut A, Sikula J: Posterior interbody fusion using laminectomy bone and transpedicular screw fixation in the treatment of lumbar spondylolisthesis. Surg Neurol, 53 (2-7):  2000, IF: 1.018 – CI: 3

 

  1. Tratamentul medicamentos bolnavilor neurochirurgicali – vezi bibliografia

 

  • Gáspár A., Kardos Sz., Andrási M., Klekner Á.: Capillary electrophoresis for the direct determination of cephalosporinsinclinical samples. Chromatographia 54: 109-114, 2002 IF: 1.317 
  • Klekner Á., A.Gáspár, S.Kardos, J.Szabó, Gy.Csécsei: Cefazolin prophylaxis in neurosurgery monitored by capillary electrophoresis, J Neurosurg Anesth, 15: 249-254, 2003 IF: 0.739 
  • Klekner A, Bagyi K, Bognar L, Gaspar A, Andrasi M, and Szabo J: Penetration of Cephalosporins into the Sputum in Nosocomial Bronchopneumonia. J Clin Microbiol, 2006 Sep; 44(9):3418-21 IF: 3.44
  • Andrasi M, Gaspar A, Klekner A: Analysis of cephalosporins in bronchial secretions by capillary electrophoresis after simple pre-treatment. J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Sep 13. IF: 2.175
  •  Bagyi K, Márton I, Szabó J, Andrási M, Gáspár A, Varga I, Bognár L, Klekner A: Efficacy of pre-operative cephalosporin prophylaxis in controlling pathogenic oral bacterial growth in comatose patients. J Med Microbiol. 2008 Jan 57:129-9 IF: 2.18
  • Bágyi K, Haczku A, Márton I, Szabó J, Gáspár A, Andrási M, Varga I, Tóth J, Klekner A.: Role of pathogenic oral flora in postoperative pneumonia following brain surgery. BMC Infect Dis. 2009 Jun 29; 9(1):104. (Epub ahead of print). IF: 2.54

Studii in strainatate:

1996:    Germania, Köln, Universitatea Köln Clinica Neurochirurgie – 2  saptamani

1998-1999:    Germania, Köln, Universitatea Köln Clinica Neurochirurgie,  Laboratorul neuro-oncologic  – 1 an bursa DAAD

2004:    Spania, Alicante, Miguel Hernandez University, Institutul De Anatomie, 2 saptamani

 

Proiecte  acceptate in cercetari:

 

  1. OTKA T-020128/1995, participant, 1996-1999, 1.400mii Ft
    Cond: Dr. Molnár Péter, DE OEC,  Institutul Patologic
  2. ETT 350/1996, participant, 1997-1999, 1.500 mii Ft
    Cond: Dr. Csécsei György, DE OEC, Clinica Neurochirurgie
  3. Mecenatura 2004-2006, participant, 750mii Ft
    Cond: Dr. Felszeghy Szabolcs, DE  OEC, Institutul de Anatomie
  4. ETT:  „Rolul devierilor histopatologice sistematice in diagnosticul precoce al aneurismelor cerebrale”  2003-2005,  3M Ft
    Cond: Dr. Klekner Álmos Péter
  5. OTKA:  „Examinarea rolului EGFR si a integrinelor in invazia tumorala in tumorile intracraniene”,  2005-2008,  6M Ft
    Cond: Dr. Klekner Álmos

 

Lucrari publicate: 13,                       Prezentatii, postere: 33

Factor impact cumulativ: 18.52        Citatii(fara autocitatii): 15.

 

Functii in societati:                      

  • Membru al Societatii  Ungara de Neurochirurgie
  • Membru al Societatii  Ungara de Neuropatologie
  • Membru al Societatii  Ungara  de Neuro-Oncologie
  • Membru al Societatii  Europene de Neurochirurgie

 

Interese stiintifice:   Laboratorul Neuro-Oncologic

 

  1. Tratamentul modern al tumorului cerebral – vezi bibliografia 
  • Klekner A, Ernestus RI, Röhn G, Molnár P, Csécsei Gy, Klug N: Polyamine metabolism in ependymomas. Path Int, 46, S1: 625, 1996, IF: 0.748
  • Ernestus RI, Röhn G, Schröder R, Els T, Klekner A, Paschen W, Klug N: Polyamine metabolism in brain tumours: diagnostic relevance of quantitative biochemistry. J Neurol Neurosurg Psychiatry 71: 88-92, 2001, IF: 3.024 
  • Klekner A, Röhn G, Schillinger G, Schröder R, Klug N, Ernestus RI: ODC mRNA as a prognostic factor for recurrence in meningiomas. J Neuro-oncol. 53: 67-75, 2001  IF: 1.435
  • Klekner A, Ernestus RI, Röhn G, Molnár P, Csécsei Gy, Klug N: Polyamine metabolism in ependymomas. Path Int, 46, S1: 625, 1996, IF: 0.748
  • Dabasi G, Hauser P, Kertész GP, Balázs G, Karádi Z, Constantin T, Bognar L, Klekner A, Schuler D, Garami M: Imaging of pediatric brain tumors using somatostatin analogue 111Ih-DTPA-D-Phe1-octreotide. Magy Onkol, 2007 51(3):229-234.

 

  1. Dezvoltarea tehnicii operatorie in bolile degenerativecoloanei  vertebrale – vezi bibliografia
  • Csécsei Gy, Klekner A, Sikula J: Posterior lumbar interbody fusion (PLIF) using the bony elements of the dorsal spinal segment. Acta Chir Hun, 36 (1-4): 54-56, 1997 
  • Csécsei Gy, Klekner A, Dobai J, Lajgut A, Sikula J: Posterior interbody fusion using laminectomy bone and transpedicular screw fixation in the treatment of lumbar spondylolisthesis. Surg Neurol, 53 (2-7):  2000, IF: 1.018 – CI: 3

 

  1. Tratamentul medicamentos bolnavilor neurochirurgicali – vezi bibliografia

 

  • Gáspár A., Kardos Sz., Andrási M., Klekner Á.: Capillary electrophoresis for the direct determination of cephalosporinsinclinical samples. Chromatographia 54: 109-114, 2002 IF: 1.317 
  • Klekner Á., A.Gáspár, S.Kardos, J.Szabó, Gy.Csécsei: Cefazolin prophylaxis in neurosurgery monitored by capillary electrophoresis, J Neurosurg Anesth, 15: 249-254, 2003 IF: 0.739 
  • Klekner A, Bagyi K, Bognar L, Gaspar A, Andrasi M, and Szabo J: Penetration of Cephalosporins into the Sputum in Nosocomial Bronchopneumonia. J Clin Microbiol, 2006 Sep; 44(9):3418-21 IF: 3.44
  • Andrasi M, Gaspar A, Klekner A: Analysis of cephalosporins in bronchial secretions by capillary electrophoresis after simple pre-treatment. J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Sep 13. IF: 2.175
  •  Bagyi K, Márton I, Szabó J, Andrási M, Gáspár A, Varga I, Bognár L, Klekner A: Efficacy of pre-operative cephalosporin prophylaxis in controlling pathogenic oral bacterial growth in comatose patients. J Med Microbiol. 2008 Jan 57:129-9 IF: 2.18